Zofenopril Other names: Zofenoprilum

Chemical formula: C₂₂H₂₃NO₄S₂  Molecular mass: 429.55 g/mol  PubChem compound: 92400

Therapeutic indications

Zofenopril is indicated for:

Mild to moderate essential hypertension

Population group: only adults (18 years old or older)

Zofenopril is indicated for the treatment of mild to moderate essential hypertension.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Acute myocardial infarction

Population group: only adults (18 years old or older)

Zofenopril is indicated for the treatment initiated within the first 24 hours of patients with acute myocardial infarction with or without signs and symptoms of heart failure, who are haemodynamically stable and have not received thrombolytic therapy.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Zofenopril is contraindicated in the following cases:

Severe hepatic impairment

Hepatic failure stage IV

Pregnancy

Pregnancy

Aliskiren in diabetes mellitus or renal impairment (GFR <60ml/min/1.73m²)

Aliskiren and additionally at least one of
Diabetes mellitus



Renal failure stage 5: Kidney failure (GFR <15 mL/min/1.73 m2 or dialysis)

Angioneurotic oedema associated with ACE inhibitor

Drug-induced angioedema-urticaria and additionally ACE inhibitors, plain

Hereditary, idiopathic angioneurotic oedema

at least one of
Hereditary angioneurotic edema
Idiopathic angio-oedema

Bilateral renal artery stenosis

Bilateral renal artery stenosis

Unilateral renal artery stenosis in cases of a solitary single kidney

RAS - Renal artery stenosis

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Summary of Product Characteristics (SPC) : ZOFENOPRIL Film-coated tablet
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