ATC Group: A03AB Synthetic anticholinergics, quaternary ammonium compounds

Glycopyrronium is an inhaled long-acting muscarinic receptor antagonist (anticholinergic) for once-daily maintenance bronchodilator treatment of COPD. Glycopyrronium works by blocking the bronchoconstrictor action of acetylcholine on airway smooth muscle cells, thereby dilating the airways.

Otilonium is endowed with a marked spasmolytic action on the smooth muscle of the digestive tract.

Prifinium is an anticholinergic preferably acting at muscarinic receptors in the gastrointestinal tract. Prifinium’s mechanism of action is believed to be due to its activity as an antispasmodic agent. It is used primarily in the treatment of irritable bowel syndrome.

Propantheline inhibits parasympathetic activity by blocking the action of the neurohormone, acetylcholine, on the neuroeffector cell. This blocking action of propantheline is instrumental in reducing gastric acid secretion and gastrointestinal motor activity.