ATC Group: C01A Cardiac glycosides

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of C01A in the ATC hierarchy

Level Code Title
1 C Cardiovascular system
2 C01 Cardiac therapy
3 C01A Cardiac glycosides

Group C01A contents

Code Title
C01AA Digitalis glycosides
C01AB Scilla glycosides
C01AC Strophantus glycosides
C01AX Other cardiac glycosides

Active ingredients in C01A

Active Ingredient Description
Anthraquinone glycosides
Deslanoside
Digoxin

Digoxin increases contractility of the myocardium by direct activity. The primary action of digoxin is specifically to inhibit adenosine triphosphatase, and thus sodium-potassium (Na+ - K+) exchange activity, the altered ionic distribution across the membrane resulting in an augmented calcium ion influx and thus an increase in the availability of calcium at the time of excitation-contraction coupling. The potency of digoxin may therefore appear considerably enhanced when the extracellular potassium concentration is low, with hyperkalaemia having the opposite effect.

Lanatoside C
Metildigoxin

Metildigoxin, a methyl derivative of digoxin, is a cardiac glycoside a type of drug that can be used in the treatment of congestive heart failure and cardiac arrhythmia.

Related product monographs

Title Information Source Document Type  
DIGOXIN Solution for injection Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
DIGOXIN Tablets Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
Lanoxin 125 Tablets Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
LANOXIN Solution for injection FDA, National Drug Code (US) MPI, US: SPL/PLR
LANOXIN Tablet FDA, National Drug Code (US) MPI, US: SPL/PLR