The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.
| Level | Code | Title | |
|---|---|---|---|
1
|
C | Cardiovascular system | |
2
|
C01 | Cardiac therapy | |
3
|
C01C | Cardiac stimulants excl. cardiac glycosides | |
4
|
C01CE | Phosphodiesterase inhibitors |
| Code | Title | |
|---|---|---|
| C01CE01 | Amrinone | |
| C01CE02 | Milrinone | |
| C01CE03 | Enoximone | |
| C01CE04 | Bucladesine |
| Active Ingredient |
|---|
|
|
|
Enoximone, an imidazolone, has both positive inotropic and vasolidator properties, inhibiting cardiac phosphodiesterase III with an increase in cAMP. |
|
Milrinone is a positive inotrope and vasodilator, with little chronotropic activity. It also improves left ventricular diastolic relaxation. It is a selective inhibitor of peak III phosphodiesterase isoenzyme in cardiac and vascular muscle. It produces slight enhancement of A-V node conduction, but no other significant electrophysiological effects. |
| Document | Type | Information Source | |
|---|---|---|---|
| PERFAN Concentrate for solution for injection or infusion | MPI, EU: SmPC | Health Products Regulatory Authority (IE) | |
| PRIMACOR Solution for injection | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) |