Chemical formula: C₁₂H₉N₃O Molecular mass: 211.219 g/mol PubChem compound: 4197
Milrinone is a positive inotrope and vasodilator, with little chronotropic activity. It also improves left ventricular diastolic relaxation. It is a selective inhibitor of peak III phosphodiesterase isoenzyme in cardiac and vascular muscle. It produces slight enhancement of A-V node conduction, but no other significant electrophysiological effects.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C01CE02 | Milrinone | C Cardiovascular system → C01 Cardiac therapy → C01C Cardiac stimulants excl. cardiac glycosides → C01CE Phosphodiesterase inhibitors |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| MILNIRONE Solution for injection / infusion | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Milrinone is an active ingredient of these brands:
Brazil (BR)
Croatia (HR)Cyprus (CY)
Ecuador (EC)Estonia (EE)
Finland (FI)France (FR)
Hong Kong (HK)
Israel (IL)Japan (JP)Malta (MT)
Mexico (MX)
Netherlands (NL)
New Zealand (NZ)
Singapore (SG)
Spain (ES)
Turkey (TR)United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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