The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.
| Level | Code | Title | |
|---|---|---|---|
| 1 | C | Cardiovascular system | |
| 2 | C07 | Beta blocking agents | |
| 3 | C07A | Beta blocking agents | |
| 4 | C07AG | Alpha and beta blocking agents |
| Code | Title | |
|---|---|---|
| C07AG01 | Labetalol | |
| C07AG02 | Carvedilol |
| Active Ingredient | Description | |
|---|---|---|
| Carvedilol |
Carvedilol is a vasodilatory non-selective beta-blocker, which reduces the peripheral vascular resistance by selective alpha1-receptor blockade and suppresses the renin-angiotensin system through non-selective beta-blockade. Plasma renin activity is reduced and fluid retention is rare. |
|
| Labetalol |
Labetalol lowers the blood pressure by blocking peripheral arteriolar alphaadrenoceptors thus reducing peripheral resistance, and by concurrent betablockade, protects the heart from reflex sympathetic drive that would otherwise occur. |
| Title | Information Source | Document Type | |
|---|---|---|---|
| DILATREND Tablet | Health Products Regulatory Authority (ZA) | MPI, Generic | |
| EUCARDIC Tablet | Health Products Regulatory Authority (IE) | MPI, EU: SmPC | |
| TRANDATE Film-coated tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
