Labetalol

Chemical formula: C₁₉H₂₄N₂O₃  Molecular mass: 328.406 g/mol  PubChem compound: 3869

Active ingredient description

Labetalol lowers the blood pressure by blocking peripheral arteriolar alphaadrenoceptors thus reducing peripheral resistance, and by concurrent betablockade, protects the heart from reflex sympathetic drive that would otherwise occur.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
C07AG01 Labetalol C Cardiovascular system → C07 Beta blocking agents → C07A Beta blocking agents → C07AG Alpha and beta blocking agents
Discover more medicines within C07AG01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
TRANDATE Film-coated tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
LABELATOL Solution for injection Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 36894-69-6
DrugBank Drug: DB00598
KEGG Drug: D08106
PubChem Compound: 3869
RxNorm Ingredient: 6185
SNOMED-CT Concept: 372750000
Labetalol (substance)
UNII Identifier: R5H8897N95
LABETALOL

Medicines

Labetalol is an active ingredient of these brands:

Australia (AU)

Austria (AT)

Canada (CA)

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

Finland (FI)

  • ALBETOL as LABETALOL HYDROCHLORIDE

France (FR)

Hong Kong (HK)

Ireland (IE)

Israel (IL)

Japan (JP)

Malta (MT)

Netherlands (NL)

New Zealand (NZ)

  • HYBLOC as LABETALOL HYDROCHLORIDE
  • TRANDATE as LABETALOL HYDROCHLORIDE

Nigeria (NG)

Singapore (SG)

South Africa (ZA)

Spain (ES)

Turkey (TR)

  • LABLOL as LABETALOL HYDROCHLORIDE

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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