The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.
| Level | Code | Title | |
|---|---|---|---|
| 1 | C | Cardiovascular system | |
| 2 | C09 | Agents acting on the renin-angiotensin system | |
| 3 | C09B | ACE inhibitors, combinations | |
| 4 | C09BB | ACE inhibitors and calcium channel blockers | |
| 5 | C09BB06 | Enalapril and nitrendipine |
| Active Ingredient | Description | |
|---|---|---|
| Enalapril and Nitrendipine |
The two active substances have a complementary antihypertensive effect. Once absorbed, enalapril is hydrolyzed to enalaprilat, a substance that inhibits ACE. This inhibition results in a decrease in plasma angiotensin II, which leads to an increase in plasma renin activity and a decrease in aldosterone secretion. Enalapril has an antihypertensive effect even in cases of hypertension with low renin. Nitrendipine is a calcium antagonist of the 1-4 dihydropyridine group that acts as an antihypertensive agent. The mechanism of action of nitrendipine is based on the inhibition of the flow of calcium ions in the smooth muscle fibers of the vessels. |
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.
