The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.
| Level | Code | Title | |
|---|---|---|---|
| 1 | C | Cardiovascular system | |
| 2 | C09 | Agents acting on the renin-angiotensin system | |
| 3 | C09B | ACE inhibitors, combinations | |
| 4 | C09BX | ACE inhibitors, other combinations | |
| 5 | C09BX03 |
| Active Ingredient | Description | |
|---|---|---|
| Ramipril, Amlodipine and Hydrochlorothiazide |
Ramiprilat, the active metabolite of the prodrug ramipril, inhibits the enzyme dipeptidylcarboxypeptidase I. Decreased formation of angiotensin II and inhibition of bradykinin degradation lead to vasodilation. Amlodipine is a calcium ion influx inhibitor of the dihydropyridine group and inhibits the entry of calcium ions through the cell membrane into cardiac cells and smooth muscle fibers. Hydrochlorothiazide is a thiazide diuretic. The mechanism of antihypertensive action of thiazide diuretics is not fully understood. |
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.
