ATC Group: D03B Enzymes

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of D03B in the ATC hierarchy

Level Code Title
1 D Dermatologicals
2 D03 Preparations for treatment of wounds and ulcers
3 D03B Enzymes

Group D03B contents

Code Title
D03BA Proteolytic enzymes

Active ingredients in D03B

Active Ingredient

Collagenases are proteinases that hydrolyze collagen under physiological conditions. Collagenase clostridium histolyticum is comprised of a mixture of Class I (AUX-I) and Class II (AUX-II) clostridial collagenases in a defined mass ratio. Both collagenases effectively cleave interstitial collagen but at different sites on the molecule; additionally, they prefer different conformations (triple helical versus denatured or cleaved).

Related product monographs

Document Type Information Source  
 COLLAGENASE SANTYL Ointment MPI, US: SPL/Old FDA, National Drug Code (US)