The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.
| Level | Code | Title | |
|---|---|---|---|
| 1 | D | Dermatologicals | |
| 2 | D05 | Antipsoriatics | |
| 3 | D05A | Antipsoriatics for topical use | |
| 4 | D05AD | Psoralens for topical use |
| Code | Title | |
|---|---|---|
| D05AD01 | Trioxysalen | |
| D05AD02 | Methoxsalen |
| Active Ingredient | Description | |
|---|---|---|
| Methoxsalen |
Methoxsalen, upon photoactivation, conjugates and forms covalent bonds with DNA which leads to the formation of both monofunctional (addition to a single strand of DNA) and bifunctional adducts (crosslinking of psoralen to both strands of DNA). Reactions with proteins have also been described. The formation of photoadducts results in inhibition of DNA synthesis, cell division and epidermal turnover. |
