The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.
| Level | Code | Title | |
|---|---|---|---|
| 1 | D | Dermatologicals | |
| 2 | D10 | Anti-acne preparations | |
| 3 | D10B | Anti-acne preparations for systemic use | |
| 4 | D10BA | Retinoids for treatment of acne |
| Code | Title | |
|---|---|---|
| D10BA01 | Isotretinoin |
| Active Ingredient | Description | |
|---|---|---|
| Isotretinoin |
Isotretinoin is a stereoisomer of all-trans retinoic acid (tretinoin). The exact mechanism of action of isotretinoin has not yet been elucidated in detail, but it has been established that the improvement observed in the clinical picture of severe acne is associated with suppression of sebaceous gland activity and a histologically demonstrated reduction in the size of the sebaceous glands. Furthermore, a dermal anti-inflammatory effect of isotretinoin has been established. |
| Title | Information Source | Document Type | |
|---|---|---|---|
| ISOTRETINOIN Capsules, soft | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| ORATANE Soft capsule | Medicines and Medical Devices Safety Authority (NZ) | MPI, EU: SmPC | |
| ROACCUTANE Capsule, soft | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
