The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.
| Level | Code | Title | |
|---|---|---|---|
1
|
H | Systemic hormonal preparations, excl. Sex hormones and insulins | |
2
|
H01 | Pituitary and hypothalamic hormones and analogues | |
3
|
H01A | Anterior pituitary lobe hormones and analogues | |
4
|
H01AA | ACTH |
| Code | Title | |
|---|---|---|
| H01AA01 | Corticotropin | |
| H01AA02 | Tetracosactide |
| Active Ingredient |
|---|
|
Corticotropin is a polypeptide hormone produced and secreted by the pituitary gland. Corticotropin acts through the stimulation of cell surface ACTH receptors, which are primarily located on the adrenocortical cells. Corticotropin stimulates the cortex of the adrenal gland and boosts the synthesis of corticosteroids, mainly glucocorticoids but also sex steroids (androgens). |
|
Tetracosactide acetate consists of the first 24 amino acids occurring in the natural corticotropic hormone (ACTH) sequence and displays the same physiological properties as ACTH. In the adrenal cortex, it stimulates the biosynthesis of glucocorticoids, mineralocorticoids, and, to a lesser extent, androgens, which explains its therapeutic effect in conditions responsive to glucocorticoid treatment. |
| Document | Type | Information Source | |
|---|---|---|---|
| ACTHAR Gel | MPI, US: SPL/PLR | FDA, National Drug Code (US) | |
| ACTHREL Powder for solution for injection | MPI, US: SPL/Old | FDA, National Drug Code (US) | |
| CORTROSYN Powder for solution for injection | MPI, US: SPL/Old | FDA, National Drug Code (US) | |
| SYNACTHEN DEPOT Suspension for injection | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) | |
| SYNACTHEN Solution for injection or infusion | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) |