Chemical formula: C₁₃₆H₂₁₀N₄₀O₃₁S Molecular mass: 2,933.49 g/mol PubChem compound: 16133751
Tetracosactide acetate consists of the first 24 amino acids occurring in the natural corticotropic hormone (ACTH) sequence and displays the same physiological properties as ACTH. In the adrenal cortex, it stimulates the biosynthesis of glucocorticoids, mineralocorticoids, and, to a lesser extent, androgens, which explains its therapeutic effect in conditions responsive to glucocorticoid treatment.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| H01AA02 | Tetracosactide | H Systemic hormonal preparations, excl. Sex hormones and insulins → H01 Pituitary and hypothalamic hormones and analogues → H01A Anterior pituitary lobe hormones and analogues → H01AA ACTH |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| CORTROSYN Powder for solution for injection | FDA, National Drug Code (US) | MPI, US: SPL/Old | |
| SYNACTHEN DEPOT Suspension for injection | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Tetracosactide is an active ingredient of these brands:
United States (US)Australia (AU)
Austria (AT)
Canada (CA)
Estonia (EE)
France (FR)
Ireland (IE)
Japan (JP)Lithuania (LT)
Malta (MT)
Netherlands (NL)
New Zealand (NZ)
Spain (ES)Turkey (TR)
United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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