The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.
| Level | Code | Title | |
|---|---|---|---|
1
|
H | Systemic hormonal preparations, excl. Sex hormones and insulins | |
2
|
H03 | Thyroid therapy | |
3
|
H03B | Antithyroid preparations | |
4
|
H03BB | Sulfur-containing imidazole derivatives |
| Code | Title | |
|---|---|---|
| H03BB01 | Carbimazole | |
| H03BB02 | Thiamazole | |
| H03BB52 | Thiamazole, combinations |
| Active Ingredient |
|---|
|
Carbimazole, a thionamide, is a pro-drug which undergoes rapid and virtually complete metabolism to the active metabolite, thiamazole, also known as methimazole. The method of action is believed to be inhibition of the organification of iodide and the coupling of iodothyronine residues which in turn suppress the synthesis of thyroid hormones. |
|
Thiamazole inhibits dose-dependently the incorporation of iodine into tyrosine and thereby the neosynthesis of thyroid hormones. This property permits symptomatic therapy of hyperthyroidism regardless of its cause. |
| Document | Type | Information Source | |
|---|---|---|---|
| NEOMERCAZOLE Tablet | MPI, EU: SmPC | Health Products Regulatory Authority (IE) | |
| TAPAZOLE Tablet | MPI, US: SPL/Old | FDA, National Drug Code (US) |