Thiamazole Other names: Tapazole Methimazole

Chemical formula: Câ‚„H₆Nâ‚‚S  Molecular mass: 114.169 g/mol  PubChem compound: 1349907

Active ingredient description

Thiamazole inhibits dose-dependently the incorporation of iodine into tyrosine and thereby the neosynthesis of thyroid hormones. This property permits symptomatic therapy of hyperthyroidism regardless of its cause.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
H03BB02 Thiamazole H Systemic hormonal preparations, excl. Sex hormones and insulins → H03 Thyroid therapy → H03B Antithyroid preparations → H03BB Sulfur-containing imidazole derivatives
Discover more medicines within H03BB02

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
THYROZOL Film-coated tablet European Medicines Agency (EU) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 60-56-0
DrugBank Drug: DB00763
KEGG Drug: D00401
PubChem Compound: 1349907
RxNorm Ingredient: 6835
SNOMED-CT Concept: 37656002
Thiamazole (substance)
UNII Identifier: 554Z48XN5E
METHIMAZOLE

Medicines

Thiamazole is an active ingredient of these brands:

United States (US)

Brazil (BR)

Canada (CA)

Croatia (HR)

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

France (FR)

Germany (DE)

Hong Kong (HK)

Israel (IL)

Japan (JP)

Lithuania (LT)

Mexico (MX)

Netherlands (NL)

Poland (PL)

Romania (RO)

Singapore (SG)

Spain (ES)

Tunisia (TN)

Turkey (TR)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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