The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.
| Level | Code | Title | |
|---|---|---|---|
| 1 | J | Antiinfectives for systemic use | |
| 2 | J01 | Antibacterials for systemic use | |
| 3 | J01X | Other antibacterials | |
| 4 | J01XB | Polymyxins |
| Code | Title | |
|---|---|---|
| J01XB01 | Colistin | |
| J01XB02 | Polymyxin B |
| Active Ingredient | Description | |
|---|---|---|
| Colistimethate |
Colistimethate is a cyclic polypeptide antibacterial active substance that is derived from Bacillus polymyxa var colistinus and belongs to the polymyxin group. Polymyxins work by damaging the cell membrane and the resulting physiological effects are lethal to the bacterium. Polymyxins are selective for Gram-negative bacteria that have a hydrophobic outer membrane. |
|
| Colistin |
Colistin is a cyclic polypeptide antibacterial agent belonging to the polymyxin group. Polymyxins work by damaging the cell membrane and the resulting physiological effects are lethal to the bacterium. Polymyxins are selective for aerobic Gram-negative bacteria that have a hydrophobic outer membrane. |
|
| Polymyxin B |
Polymixin B is bactericidal against a wide range of gram negative bacilli. It exerts a bactericidal effect by binding to acid phospholipids in the cell wall and membranes of the bacterium, thereby rendering ineffective the osmotic barrier normally provided by the cell membrane. |
| Title | Information Source | Document Type | |
|---|---|---|---|
| COLOBREATHE Inhalation powder, hard capsule | European Medicines Agency (EU) | MPI, EU: SmPC | |
| COLOMYCIN Powder for solution for injection / infusion / inhalation | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| COLY-MYCIN M Solution for injection | FDA, National Drug Code (US) | MPI, US: SPL/Old | |
| PROMIXIN Powder for nebuliser solution | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
