ATC Group: J01XX12 Lefamulin

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of J01XX12 in the ATC hierarchy

Level Code Title
1 J Antiinfectives for systemic use
2 J01 Antibacterials for systemic use
3 J01X Other antibacterials
4 J01XX Other antibacterials
5 J01XX12

Active ingredients in J01XX12

Active Ingredient

Lefamulin is a pleuromutilin antibacterial agent. It inhibits bacterial protein synthesis by interacting with the A- and P- sites of the peptidyl transferase centre (PTC) in the central part of domain V of the 23S rRNA of the 50S ribosomal subunit, preventing correct positioning of the tRNA.

Related product monographs

Document Type Information Source  
 XENLETA Concentrate and solvent for solution for infusion MPI, EU: SmPC European Medicines Agency (EU)
 XENLETA Film-coated tablet MPI, EU: SmPC European Medicines Agency (EU)
 XENLETA Solution for injection / Film-coated tablet MPI, US: SPL/PLR FDA, National Drug Code (US)

United States medicines

Medicines classified under this ATC code globally

Austria (AT)

Croatia (HR)

Estonia (EE)

Ireland (IE)

Italy (IT)

Lithuania (LT)

Poland (PL)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.