ATC Group: J04AK08 Pretomanid

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of J04AK08 in the ATC hierarchy

Level Code Title
1 J Antiinfectives for systemic use
2 J04 Antimycobacterials
3 J04A Drugs for treatment of tuberculosis
4 J04AK Other drugs for treatment of tuberculosis
5 J04AK08

Active ingredients in J04AK08

Active Ingredient Description
Pretomanid

The mechanism of action of pretomanid is thought to involve inhibition of the synthesis of cell wall lipids under aerobic conditions and generation of reactive nitrogen species under anaerobic conditions. Reductive activation of pretomanid by a mycobacterial deazaflavin (F420)-dependent nitro-reductase is required for activity under both aerobic and anaerobic conditions.

Related product monographs

Title Information Source Document Type  
DOVPRELA Tablet European Medicines Agency (EU) MPI, EU: SmPC

Medicines in this ATC group

Croatia (HR)

Estonia (EE)

France (FR)

Italy (IT)

Lithuania (LT)

Poland (PL)

South Africa (ZA)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.