The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.
| Level | Code | Title | |
|---|---|---|---|
| 1 | L | Antineoplastic and immunomodulating agents | |
| 2 | L02 | Endocrine therapy | |
| 3 | L02B | Hormone antagonists and related agents | |
| 4 | L02BG | Aromatase inhibitors |
| Code | Title | |
|---|---|---|
| L02BG01 | Aminogluthetimide | |
| L02BG02 | Formestane | |
| L02BG03 | Anastrozole | |
| L02BG04 | Letrozole | |
| L02BG05 | Vorozole | |
| L02BG06 | Exemestane |
| Active Ingredient | Description | |
|---|---|---|
| Anastrozole |
Anastrozole is a potent and highly selective non-steroidal aromatase inhibitor. It inhibits the enzyme aromatase, which is responsible for converting androgens to estrogens. Anastrozole is a drug indicated in the treatment of breast cancer in post-menopausal women. |
|
| Exemestane |
Exemestane is an irreversible, steroidal aromatase inhibitor, structurally related to the natural substrate androstenedione. |
|
| Formestane |
|
|
| Letrozole |
Letrozole is a non-steroidal aromatase inhibitor. It inhibits the aromatase enzyme by competitively binding to the haem of the aromatase cytochrome P450, resulting in a reduction of oestrogen biosynthesis in all tissues where present. |
| Title | Information Source | Document Type | |
|---|---|---|---|
| AREMED Film-coated tablet | Υπουργείο Υγείας (CY) | MPI, EU: SmPC | |
| ARIMIDEX Film-coated tablets | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| AROMASIN Coated tablets | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| FEMARA Film-coated tablet | Health Products Regulatory Authority (IE) | MPI, EU: SmPC | |
| LETROLE Film-coated tablet | Medicines and Medical Devices Safety Authority (NZ) | MPI, EU: SmPC | |
| SADERON Film-coated tablet | Υπουργείο Υγείας (CY) | MPI, EU: SmPC |
