The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.
| Level | Code | Title | |
|---|---|---|---|
1
|
L | Antineoplastic and immunomodulating agents | |
2
|
L02 | Endocrine therapy | |
3
|
L02B | Hormone antagonists and related agents | |
4
|
L02BG | Aromatase inhibitors | |
5
|
L02BG04 | Letrozole |
The DDD is the assumed average maintenance dose per day for a drug used for its main indication in adults. The DDD is a unit of measurement and does not necessarily reflect the recommended or Prescribed Daily Dose. Therapeutic doses for individual patients and patient groups will often differ from the DDD as they will be based on individual characteristics (such as age, weight, ethnic differences, type and severity of disease) and pharmacokinetic considerations.
| Code | Route | Amount | Notes |
|---|---|---|---|
| ORAL | Oral | 2.5 mg |
| Active Ingredient |
|---|
|
Letrozole is a non-steroidal aromatase inhibitor. It inhibits the aromatase enzyme by competitively binding to the haem of the aromatase cytochrome P450, resulting in a reduction of oestrogen biosynthesis in all tissues where present. |
| Document | Type | Information Source | |
|---|---|---|---|
| FEMARA Film-coated tablet | MPI, EU: SmPC | Health Products Regulatory Authority (IE) | |
| LETROLE Film-coated tablet | MPI, EU: SmPC | Medicines and Medical Devices Safety Authority (NZ) | |
| SADERON Film-coated tablet | MPI, EU: SmPC | Υπουργείο Υγείας (CY) |
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.