The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.
| Level | Code | Title | |
|---|---|---|---|
1
|
M | Musculo-skeletal system | |
2
|
M03 | Muscle relaxants | |
3
|
M03A | Muscle relaxants, peripherally acting agents | |
4
|
M03AX | Other muscle relaxants, peripherally acting agents | |
5
|
M03AX01 | Botulinum toxin |
| Active Ingredient |
|---|
|
Botulinum toxin type A is a protein complex derived from Clostridium botulinum. The protein consists of type A neurotoxin and several other proteins. Under physiological conditions it is presumed that the complex dissociates and releases the pure neurotoxin. Intramuscular injection of the neurotoxin complex blocks cholinergic transport at the neuromuscular junction by preventing the release of acetylcholine. The nerve endings of the neuromuscular junction no longer respond to nerve impulses and secretion of the chemotransmitter is prevented (chemical denervation). |
|
Botulinum toxin type B is a neuromuscular blocking agent indicated for the treatment of cervical dystonia. When injected directly into a muscle, it causes a localised paralysis that gradually reverses over time. |
| Document | Type | Information Source | |
|---|---|---|---|
| ALLUZIENCE Solution for injection | MPI, EU: SmPC | Health Products Regulatory Authority (IE) | |
| AZZALURE Powder for solution for injection | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) | |
| BOTOX Powder for solution for injection | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) | |
| LETYBO Powder for solution | MPI, US: SPL/PLR | FDA, National Drug Code (US) | |
| NEUROBLOC Solution for injection | MPI, EU: SmPC | European Medicines Agency (EU) | |
| NUCEIVA Powder for solution for injection | MPI, EU: SmPC | European Medicines Agency (EU) | |
| XEOMIN Powder for solution for injection | MPI, US: SPL/PLR | FDA, National Drug Code (US) |
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.