The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.
| Level | Code | Title | |
|---|---|---|---|
1
|
N | Nervous system | |
2
|
N02 | Analgesics | |
3
|
N02A | Opioids | |
4
|
N02AX | Other opioids | |
5
|
N02AX02 | Tramadol |
The DDD is the assumed average maintenance dose per day for a drug used for its main indication in adults. The DDD is a unit of measurement and does not necessarily reflect the recommended or Prescribed Daily Dose. Therapeutic doses for individual patients and patient groups will often differ from the DDD as they will be based on individual characteristics (such as age, weight, ethnic differences, type and severity of disease) and pharmacokinetic considerations.
| Code | Route | Amount | Notes |
|---|---|---|---|
| ORAL | Oral | 0.3 g | |
| PAREN | Parenteral | 0.3 g | |
| RECTAL | Rectal | 0.3 g |
| Active Ingredient |
|---|
|
Tramadol is a centrally acting opioid analgesic. It is a non selective pure agonist at μ-, δ- and κ-opioid receptors with a higher affinity for the μ-receptor. Other mechanisms which may contribute to its analgesic effect are inhibition of neuronal reuptake of noradrenaline and enhancement of serotonin release. Tramadol has an antitussive effect. In contrast to morphine, analgesic doses of tramadol over a wide range have no respiratory depressant effect. |
| Document | Type | Information Source | |
|---|---|---|---|
| DOLTREX Film-coated tablet | MPI, Generic | Health Products Regulatory Authority (ZA) | |
| TRAMAL Capsule, Solution for injection, Tablet | MPI, EU: SmPC | Medicines and Medical Devices Safety Authority (NZ) | |
| ULTRAM Coated tablet | MPI, US: SPL/PLR | FDA, National Drug Code (US) | |
| ZYDOL Soluble tablet | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) | |
| ZYDOL Solution for injection or infusion | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) | |
| ZYTRAM XL Controlled release tablet | MPI, CA: SPM | Health Products and Food Branch (CA) |
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.