ATC Group: N02BF Gabapentinoids

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of N02BF in the ATC hierarchy

Level Code Title
1 N Nervous system
2 N02 Analgesics
3 N02B Other analgesics and antipyretics
4 N02BF Gabapentinoids

Group N02BF contents

Code Title
N02BF01 Gabapentin
N02BF02 Pregabalin
N02BF03

Active ingredients in N02BF

Active Ingredient

Gabapentin readily enters the brain and prevents seizures in a number of animal models of epilepsy. Gabapentin binds with high affinity to the α2δ (alpha-2-delta) subunit of voltage-gated calcium channels and it is proposed that binding to the α2δ subunit may be involved in gabapentin’s anti-seizure effects in animals.

Pregabalin binds to an auxiliary subunit (α2-δ protein) of voltage-gated calcium channels in the central nervous system.

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