Pregabalin

Chemical formula: C₈H₁₇NO₂  Molecular mass: 159.226 g/mol  PubChem compound: 5486971

Active ingredient description

Pregabalin binds to an auxiliary subunit (α2-δ protein) of voltage-gated calcium channels in the central nervous system.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
N02BF02 Pregabalin N Nervous system → N02 Analgesics → N02B Other analgesics and antipyretics → N02BF Gabapentinoids
Discover more medicines within N02BF02

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
LYRICA Hard capsule European Medicines Agency (EU) MPI, EU: SmPC
REGADEX Hard capsule Health Sciences Authority (SG) MPI, Generic

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 148553-50-8
DrugBank Drug: DB00230
KEGG Drug: D02716
PubChem Compound: 5486971
RxNorm Ingredient: 187832
SNOMED-CT Concept: 415159003
Product containing pregabalin (medicinal product)
SNOMED-CT Concept: 415160008
Pregabalin (substance)
UNII Identifier: 55JG375S6M
PREGABALIN

Medicines

Pregabalin is an active ingredient of these brands:

United States (US)

Albania (AL)

Canada (CA)

Finland (FI)

France (FR)

Ireland (IE)

Israel (IL)

Japan (JP)

Mexico (MX)

Netherlands (NL)

New Zealand (NZ)

Romania (RO)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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