ATC Group: P01AB Nitroimidazole derivatives

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of P01AB in the ATC hierarchy

Level Code Title
1 P Antiparasitic products, insecticides and repellents
2 P01 Antiprotozoals
3 P01A Agents against amoebiasis and other protozoal diseases
4 P01AB Nitroimidazole derivatives

Group P01AB contents

Code Title
P01AB01 Metronidazole
P01AB02 Tinidazole
P01AB03 Ornidazole
P01AB04 Azanidazole
P01AB05 Propenidazole
P01AB06 Nimorazole
P01AB07 Secnidazole
P01AB08
P01AB51 Metronidazole and furazolidone
P01AB52
P01AB53

Active ingredients in P01AB

Active Ingredient

Metronidazole is an anti-infectious drug belonging to the pharmacotherapeutic group of nitroimidazole derivatives, which have effect mainly on strict anaerobes. This effect is probably caused by interaction with DNS and different metabolites.

Ornidazole is indicated for the treatment of Bacterial vaginosis. It is effective against Trichomonas vaginalis, Entamoeba histolytica and Giardia lamblia (Giardia intestinalis), and also against certain anaerobic bacteria such as Bacteroides and Clostridium spp., Fusobacterium spp., and anaerobic cocci.

Secnidazole is a nitroimidazole antimicrobial drug that displays selectivity against many anaerobic Gram-positive and Gram-negative bacteria and protozoa.

Tinidazole is active against both protozoa and obligate anaerobic bacteria. The activity against protozoa involves Trichomonas vaginalis, Entamoeba histolytica and Giardia lamblia. The mode of action of tinidazole against anaerobic bacteria and protozoa involves penetration of the drug into the cell of the micro-organism and subsequent damage of DNA strands or inhibition of their synthesis.

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