The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.
| Level | Code | Title | |
|---|---|---|---|
1
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P | Antiparasitic products, insecticides and repellents | |
2
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P01 | Antiprotozoals | |
3
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P01C | Agents against leishmaniasis and trypanosomiasis |
| Code | Title | |
|---|---|---|
| P01CA | Nitroimidazole derivatives | |
| P01CB | Antimony compounds | |
| P01CC | Nitrofuran derivatives | |
| P01CD | Arsenic compounds | |
| P01CX | Other agents against leishmaniasis and trypanosomiasis |
| Active Ingredient |
|---|
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Eflornithine irreversibly inhibits ornithine decarboxylase, an enzyme involved in the production of the hair shaft by the hair follicle. Eflornithine has been shown to reduce the rate of hair growth. |
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Miltefosine has a marked direct antileishmanial activity in vitro and in animal models. Leishmania donovani was the most sensitive species in promastigote and amastigote test systems. |
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Nifurtimox is an antiprotozoal drug. It is used in pediatric patients for the treatment of Chagas disease (American Trypanosomiasis) caused by Trypanosoma cruzi. Nifurtimox exposure-response relationships and the time course of pharmacodynamics response are unknown. |
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Pentamidine isetionate is an aromatic diamine. It is an antiprotozoal agent which acts by interfering with DNA and folate transformation, and by the inhibition of RNA and protein synthesis. |
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| Document | Type | Information Source | |
|---|---|---|---|
| GASTROGRAFIN Gastroenteral solution | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) | |
| PENTACARINAT Powder for reconstitution | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) |