Pentamidine Other names: 1,3-bis(4-amidinophenoxy)pentane 4, 4'-Diamidinodiphenoxypentane Pentamidine isethionate

Chemical formula: C₁₉H₂₄N₄O₂  Molecular mass: 340.42 g/mol  PubChem compound: 4735

Active ingredient description

Pentamidine isetionate is an aromatic diamine. It is an antiprotozoal agent which acts by interfering with DNA and folate transformation, and by the inhibition of RNA and protein synthesis.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
P01CX01 Pentamidine isethionate P Antiparasitic products, insecticides and repellents → P01 Antiprotozoals → P01C Agents against leishmaniasis and trypanosomiasis → P01CX Other agents against leishmaniasis and trypanosomiasis
Discover more medicines within P01CX01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
PENTACARINAT Powder for reconstitution Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 100-33-4
DrugBank Drug: DB00738
PubChem Compound: 4735
RxNorm Ingredient: 7995
SNOMED-CT Concept: 372699006
Pentamidine (substance)
UNII Identifier: 673LC5J4LQ
PENTAMIDINE

Medicines

Pentamidine is an active ingredient of these brands:

United States (US)

Estonia (EE)

Hong Kong (HK)

Japan (JP)

Malta (MT)

Netherlands (NL)

New Zealand (NZ)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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