ATC Group: R01AX Other nasal preparations

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of R01AX in the ATC hierarchy

Level Code Title
1 R Respiratory system
2 R01 Nasal preparations
3 R01A Decongestants and other nasal preparations for topical use
4 R01AX Other nasal preparations

Group R01AX contents

Code Title
R01AX01 Calcium hexamine thiocyanate
R01AX02 Retinol
R01AX03 Ipratropium bromide
R01AX05 Ritiometan
R01AX06 Mupirocin
R01AX07 Hexamidine
R01AX08 Framycetin
R01AX09 Hyaluronic acid
R01AX10 Various
R01AX30 Combinations

Active ingredients in R01AX

Active Ingredient Description
Framycetin
Hexamidine
Hyaluronate sodium
Ipratropium

Ipratropium is a quaternary ammonium compound with anticholinergic (parasympatholytic) properties. Ipratropium appears to inhibit vagally mediated reflexes by antagonising the action of acetylcholine, the transmitter agent released from the vagus nerve. Anticholinergics prevent the increase in intracellular concentration of Ca++, which is caused by interaction of acetylcholine with the muscarinic receptor on bronchial smooth muscle. Ca++ release is mediated by the second messenger system consisting of IP3 (inositol triphosphate) and DAG (diacylglycerol).

Mupirocin

Mupirocin is a novel antibiotic produced through fermentation by Pseudomonas fluorescens. Mupirocin inhibits isoleucyl transfer-RNA synthetase, thereby arresting bacterial protein synthesis. Mupirocin has bacteriostatic properties at minimum inhibitory concentrations and bactericidal properties at the higher concentrations reached when applied locally.

Ritiometan

Related product monographs

Title Information Source Document Type  
ATROVENT HFA Inhalation aerosol, metered FDA, National Drug Code (US) MPI, US: SPL/PLR
ATROVENT Nebuliser solution Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
BACTROBAN 2% Cream Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
BACTROBAN Nasal ointment Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
IPRAVENT Pressurised inhalation, solution Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
MURIPOCIN 2% w/w Ointment Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC