Chemical formula: C₂₆H₄₄O₉ Molecular mass: 500.622 g/mol PubChem compound: 446596
Mupirocin is a novel antibiotic produced through fermentation by Pseudomonas fluorescens. Mupirocin inhibits isoleucyl transfer-RNA synthetase, thereby arresting bacterial protein synthesis. Mupirocin has bacteriostatic properties at minimum inhibitory concentrations and bactericidal properties at the higher concentrations reached when applied locally.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| D06AX09 | Mupirocin | D Dermatologicals → D06 Antibiotics and chemotherapeutics for dermatological use → D06A Antibiotics for topical use → D06AX Other antibiotics for topical use |
| R01AX06 | Mupirocin | R Respiratory system → R01 Nasal preparations → R01A Decongestants and other nasal preparations for topical use → R01AX Other nasal preparations |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| BACTROBAN Nasal ointment | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| MURIPOCIN 2% w/w Ointment | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| BACTROBAN 2% Cream | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Mupirocin is an active ingredient of these brands:
Australia (AU)
Austria (AT)
Canada (CA)
Ecuador (EC)Estonia (EE)
Finland (FI)
Hong Kong (HK)Ireland (IE)
Israel (IL)
Japan (JP)
Malta (MT)
Mexico (MX)
Tunisia (TN)
Turkey (TR)United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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