Mupirocin

Chemical formula: C₂₆H₄₄O₉  Molecular mass: 500.622 g/mol  PubChem compound: 446596

Active ingredient description

Mupirocin is a novel antibiotic produced through fermentation by Pseudomonas fluorescens. Mupirocin inhibits isoleucyl transfer-RNA synthetase, thereby arresting bacterial protein synthesis. Mupirocin has bacteriostatic properties at minimum inhibitory concentrations and bactericidal properties at the higher concentrations reached when applied locally.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
D06AX09 Mupirocin D Dermatologicals → D06 Antibiotics and chemotherapeutics for dermatological use → D06A Antibiotics for topical use → D06AX Other antibiotics for topical use
Discover more medicines within D06AX09
R01AX06 Mupirocin R Respiratory system → R01 Nasal preparations → R01A Decongestants and other nasal preparations for topical use → R01AX Other nasal preparations
Discover more medicines within R01AX06

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
BACTROBAN 2% Cream Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
BACTROBAN Nasal ointment Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
MURIPOCIN 2% w/w Ointment Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 12650-69-0
DrugBank Drug: DB00410
KEGG Drug: D01076
PubChem Compound: 446596
RxNorm Ingredient: 42372
SNOMED-CT Concept: 387397004
Mupirocin (substance)
UNII Identifier: D0GX863OA5
MUPIROCIN

Medicines

Mupirocin is an active ingredient of these brands:

United States (US)

Australia (AU)

Austria (AT)

Brazil (BR)

Canada (CA)

Croatia (HR)

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

Finland (FI)

France (FR)

Hong Kong (HK)

Ireland (IE)

Israel (IL)

Japan (JP)

Malta (MT)

Mexico (MX)

New Zealand (NZ)

Nigeria (NG)

Poland (PL)

Singapore (SG)

South Africa (ZA)

Spain (ES)

Tunisia (TN)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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