ATC Group: R07AX30 Ivacaftor and lumacaftor

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of R07AX30 in the ATC hierarchy

Level Code Title
1 R Respiratory system
2 R07 Other respiratory system products
3 R07A Other respiratory system products
4 R07AX Other respiratory system products
5 R07AX30 Ivacaftor and lumacaftor

Active ingredients in R07AX30

Active Ingredient Description
Ivacaftor and Lumacaftor

The combined effect of lumacaftor and ivacaftor is increased quantity and function of F508delCFTR at the cell surface, resulting in increased chloride ion transport. The exact mechanisms by which lumacaftor improves cellular processing and trafficking of F508delCFTR and ivacaftor potentiates F508del-CFTR are not known.

Lumacaftor

Related product monographs

Title Information Source Document Type  
ORKAMBI Film-coated tablet European Medicines Agency (EU) MPI, EU: SmPC
ORKAMBI Granules European Medicines Agency (EU) MPI, EU: SmPC

Medicines in this ATC group

United States (US)

Australia (AU)

Austria (AT)

Brazil (BR)

Canada (CA)

Croatia (HR)

Ecuador (EC)

Estonia (EE)

Finland (FI)

France (FR)

Ireland (IE)

Israel (IL)

Italy (IT)

Lithuania (LT)

Netherlands (NL)

Poland (PL)

Romania (RO)

Spain (ES)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.