The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.
| Level | Code | Title | |
|---|---|---|---|
1
|
V | Various | |
2
|
V03 | All other therapeutic products | |
3
|
V03A | All other therapeutic products | |
4
|
V03AC | Iron chelating agents |
| Code | Title | |
|---|---|---|
| V03AC01 | Deferoxamine | |
| V03AC02 | Deferiprone | |
| V03AC03 | Deferasirox |
| Active Ingredient |
|---|
|
Deferasirox is an orally active chelator that is highly selective for iron (III). It is a tridentate ligand that binds iron with high affinity in a 2:1 ratio. Deferasirox promotes excretion of iron, primarily in the faeces. |
|
Deferiprone is a bidentate ligand which binds iron in a 3:1 molar ratio. Deferiprone monotherapy is indicated for the treatment of iron overload in patients with thalassaemia major when current chelation therapy is contraindicated or inadequate. |
|
Deferoxamine is a chelating agent for trivalent iron and aluminium ions. The resulting chelates are stable and non-toxic. |
| Document | Type | Information Source | |
|---|---|---|---|
| DESFERAL Sterile, lyophilised powder | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) | |
| EXJADE Dispersible tablet | MPI, EU: SmPC | European Medicines Agency (EU) | |
| EXJADE Film-coated tablet | MPI, EU: SmPC | European Medicines Agency (EU) | |
| EXJADE Granules in sachet | MPI, EU: SmPC | European Medicines Agency (EU) | |
| Ferriprox 100 mg/ml oral solution | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) | |
| FERRIPROX Film-coated tablet | MPI, EU: SmPC | European Medicines Agency (EU) | |
| JADENU Film-coated tablet / Granules | MPI, US: SPL/PLR | FDA, National Drug Code (US) |