ATC Group: V10XX Various therapeutic radiopharmaceuticals

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of V10XX in the ATC hierarchy

Level Code Title
1 V Various
2 V10 Therapeutic radiopharmaceuticals
3 V10X Other therapeutic radiopharmaceuticals
4 V10XX Various therapeutic radiopharmaceuticals

Group V10XX contents

Code Title
V10XX01 Sodium phosphate (32P)
V10XX02 Ibritumomab tiuxetan [90Y]
V10XX03
V10XX04
V10XX05

Active ingredients in V10XX

Active Ingredient

Lutetium (177Lu) oxodotreotide has a high affinity for subtype 2 somatostatin receptors (sst2). It binds to malignant cells which overexpress sst2 receptors. Lutetium-177 (177Lu) is a βemitting radionuclide with a maximum penetration range in tissue of 2.2 mm (mean penetration range of 0.67 mm), which is sufficient to kill targeted tumour cells with a limited effect on neighbouring normal cells.

Radium-223 dichloride mimics calcium and selectively targets bone, specifically areas of bone metastases, by forming complexes with the bone mineral hydroxyapatite. Radium-223 dichloride monotherapy or in combination with luteinising hormone releasing hormone (LHRH) analogue is indicated for the treatment of adult patients with metastatic castration-resistant prostate cancer (mCRPC).

Related product monographs

Document Type Information Source  
 LUTATHERA Solution for infusion MPI, EU: SmPC European Medicines Agency (EU)
 LUTATHERA Solution for injection MPI, US: SPL/PLR FDA, National Drug Code (US)
 PLUVICTO Solution for injection/infusion MPI, EU: SmPC European Medicines Agency (EU)
 XOFIGO Solution for injection MPI, EU: SmPC European Medicines Agency (EU)
 ZEVALIN Kit for radiopharmaceutical preparations for infusion MPI, EU: SmPC European Medicines Agency (EU)