This brand name is authorized in Ecuador
The drug ASMADRIL contains a combination of these active pharmaceutical ingredients (APIs):
1
Phenylephrine
UNII 04JA59TNSJ - PHENYLEPHRINE HYDROCHLORIDE
|
Phenylephrine is a sympathomimetic agent with mainly direct effects on adrenergic receptors. It has predominantly alpha adrenergic activity and is without stimulating effects on the central nervous system. The sympathomimetic effect of phenylephrine produces vasoconstriction which in turn relieves nasal congestion. |
2
Theophylline
UNII 0I55128JYK - THEOPHYLLINE ANHYDROUS
|
Theophylline is a bronchodilator. In addition it affects the function of a number of cells involved in the inflammatory processes associated with asthma and chronic obstructive airways disease. Theophylline stimulates the myocardium and produces a diminution of venous pressure in congestive heart failure leading to marked increase in cardiac output. |
3
Guaifenesin
UNII 495W7451VQ - GUAIFENESIN
|
Guaifenesin is an expectorant the action of which promotes or facilitates the removal of secretions from the respiratory tract. The precise mechanism of action of guaifenesin is not known; however, it is thought to act as an expectorant by increasing the volume and reducing the viscosity of secretions in the trachea and bronchi. In turn, this may increase the efficiency of the cough reflex and facilitate removal of the secretions. Guaifenesin is over-the-counter drug for the treatment of cough and common cold. |
4
Cetirizine
UNII 64O047KTOA - CETIRIZINE HYDROCHLORIDE
|
Cetirizine, a human metabolite of hydroxyzine, is a potent and selective antagonist of peripheral H1-receptors. In vitro receptor binding studies have shown no measurable affinity for other than ฮ1-receptors. |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
ATC code | Group title | Classification |
---|---|---|
R01BA53 | Phenylephrine, combinations | R Respiratory system → R01 Nasal preparations → R01B Nasal decongestants for systemic use → R01BA Sympathomimetics |
This drug has been assigned below unique identifiers within the countries it is being marketed:
Country | Identification scheme | Identifier(s) |
---|---|---|
Country: EC | Agencia Nacional de Regulaciรณn, Control y Vigilancia Sanitaria | Identifier(s): 1028-MEN-0417, 780-MEN-0416 |
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