Chemical formula: C₂₁H₂₅ClN₂O₃ Molecular mass: 388.888 g/mol PubChem compound: 2678
Cetirizine, a human metabolite of hydroxyzine, is a potent and selective antagonist of peripheral H1-receptors. In vitro receptor binding studies have shown no measurable affinity for other than Η1-receptors.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
ATC code | Group title | Classification |
---|---|---|
R06AE07 | Cetirizine | R Respiratory system → R06 Antihistamines for systemic use → R06A Antihistamines for systemic use → R06AE Piperazine derivatives |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
Title | Information Source | Document Type | |
---|---|---|---|
REACTINE Tablet, Capsule, Syrup | Health Products and Food Branch (CA) | MPI, CA: SPM | |
ZIRTEK ALLERGY Film-coated tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Cetirizine is an active ingredient of these brands:
Albania (AL)Australia (AU)
Austria (AT)
Brazil (BR)Canada (CA)
Croatia (HR)
Cyprus (CY)Ecuador (EC)
Estonia (EE)Finland (FI)France (FR)Germany (DE)Hong Kong (HK)
Ireland (IE)
Italy (IT)
Japan (JP)
Lithuania (LT)
Malta (MT)
Mexico (MX)
New Zealand (NZ)Nigeria (NG)
Poland (PL)
Romania (RO)Singapore (SG)
South Africa (ZA)
Spain (ES)
Tunisia (TN)Turkey (TR)
United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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