Theophylline Other names: Dimethylxanthine

Chemical formula: C₇H₈N₄O₂  Molecular mass: 180.164 g/mol  PubChem compound: 2153

Active ingredient description

Theophylline is a bronchodilator. In addition it affects the function of a number of cells involved in the inflammatory processes associated with asthma and chronic obstructive airways disease. Theophylline stimulates the myocardium and produces a diminution of venous pressure in congestive heart failure leading to marked increase in cardiac output.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
R03DA04 Theophylline R Respiratory system → R03 Drugs for obstructive airway diseases → R03D Other systemic drugs for obstructive airway diseases → R03DA Xanthines
Discover more medicines within R03DA04

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
UNIPHYLLIN CONTINUS Prolonged release tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
THEOPHYLLINE IN DEXTROSE Solution for injection FDA, National Drug Code (US) MPI, US: SPL/Old

Structural formula

Graphic representation of the active ingredient's molecular structure

3D molecular structure

3D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 58-55-9
CAS Substance: 5967-84-0
DrugBank Drug: DB00277
KEGG Drug: D00371
PubChem Compound: 2153
RxNorm Ingredient: 10438
SNOMED-CT Concept: 255657001
Theophylline (substance)
SNOMED-CT Concept: 372810006
Theophylline (substance)
UNII Identifier: C137DTR5RG
THEOPHYLLINE

Medicines

Theophylline is an active ingredient of these brands:

United States (US)

Australia (AU)

Brazil (BR)

Canada (CA)

Croatia (HR)

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

Finland (FI)

France (FR)

Germany (DE)

Hong Kong (HK)

Ireland (IE)

Israel (IL)

Japan (JP)

Lithuania (LT)

Malta (MT)

Mexico (MX)

Netherlands (NL)

New Zealand (NZ)

Nigeria (NG)

Poland (PL)

Romania (RO)

Singapore (SG)

South Africa (ZA)

Spain (ES)

Tunisia (TN)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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