This brand name is authorized in Turkey
The drug BERMAXIN contains a combination of these active pharmaceutical ingredients (APIs):
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1
Idebenone
UNII HB6PN45W4J - IDEBENONE
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Idebenone is an anti-oxidant assumed to be capable of transferring electrons directly to complex III of the mitochondrial electron transport chain, thereby restoring cellular energy (ATP) generation under experimental conditions of complex I deficiency. Similarly, in LHON idebenone can transfer electrons directly to complex III of the electron transport chain, thereby bypassing complex I which is affected by all three primary mtDNA mutations causing LHON, and restoring cellular ATP generation. |
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2
Donepezil
UNII 3O2T2PJ89D - DONEPEZIL HYDROCHLORIDE
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Donepezil hydrochloride is a specific and reversible inhibitor of acetylcholinesterase, the predominant cholinesterase in the brain. Donepezil hydrochloride is in vitro over 1000 times more potent an inhibitor of this enzyme than of butyrylcholinesterase, an enzyme that is present mainly outside the central nervous system. |
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3
Memantine
UNII JY0WD0UA60 - MEMANTINE HYDROCHLORIDE
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Memantine is a voltage-dependent, moderate-affinity uncompetitive NMDA-receptor antagonist. It modulates the effects of pathologically elevated tonic levels of glutamate that may lead to neuronal dysfunction. |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| N06DX | Other anti-dementia drugs | N Nervous system → N06 Psychoanaleptics → N06D Anti-dementia drugs |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: TR | ฤฐlaรง ve Tฤฑbbi Cihaz Kurumu | Identifier(s): 8697927093004, 8697927093011 |
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