DOXIPROCT

Calcium dobesilate is a regulator of capillary functions. Calcium dobesilate acts on the capillary walls by regulating its impaired physiological functions – increased permeability and decreased resistance. It increases erythrocyte flexibility, inhibits platelet hyperaggregation and, in diabetic retinopathy, it reduces plasma and blood hyperviscosity, thus improving blood rheological properties and tissue irrigation.

Lidocaine, like other local anaesthetics, causes a reversible blockade of impulse propagation along nerve fibres by preventing the inward movement of sodium ions through the nerve membrane. Local anaesthetics of the amide-type are thought to act within the sodium channels of the nerve membrane.