EMTHEXATE

This brand name is authorized in Hong Kong, Malta, Netherlands, Singapore, Turkey, South Africa

Active ingredients

The drug EMTHEXATE contains one active pharmaceutical ingredient (API):

1 Methotrexate UNII YL5FZ2Y5U1 - METHOTREXATE

Methotrexate (4-amino-10-methylfolic acid) is a folic acid antagonist which inhibits the reduction of folic acid and increase of tissue cells. Methotrexate enters the cell through an active transport mechanism of reduced folates. As a result of polyglutamation of methotrexate caused by the folylpolyglutamylate enzyme, the duration of the cytotoxic effect of the drug substance in the cell increases. Read about Methotrexate

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code	Group title	Classification
L01BA01	Methotrexate	L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01B Antimetabolites → L01BA Folic acid analogues
Discover more medicines within L01BA01
L04AX03	Methotrexate	L Antineoplastic and immunomodulating agents → L04 Immunosuppressants → L04A Immunosuppressants → L04AX Other immunosuppressants
Discover more medicines within L04AX03

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
Country: HK	Department of Health Drug Office	Identifier(s): 27061, 27062
Country: MT	Medicines Authority	Identifier(s): AA565/81901, AA565/81902, AA565/81903
Country: NL	Z-Index G-Standaard	Identifier(s): 12309036
Country: NL	Z-Index G-Standaard, PRK	Identifier(s): 102806, 102814, 102822, 140767, 141003, 141011, 1686
Country: SG	Health Sciences Authority	Identifier(s): 12414P
Country: TR	İlaç ve Tıbbi Cihaz Kurumu	Identifier(s): 8699638012053
Country: ZA	Health Products Regulatory Authority	Identifier(s): S/26/346, S/26/347, S/26/348, S/26/349, S/26/350