ATC Group: L01BA01 Methotrexate

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of L01BA01 in the ATC hierarchy

Level Code Title
1 L Antineoplastic and immunomodulating agents
2 L01 Antineoplastic agents
3 L01B Antimetabolites
4 L01BA Folic acid analogues
5 L01BA01 Methotrexate

Active ingredients in L01BA01

Active Ingredient Description
Methotrexate

Methotrexate (4-amino-10-methylfolic acid) is a folic acid antagonist which inhibits the reduction of folic acid and increase of tissue cells. Methotrexate enters the cell through an active transport mechanism of reduced folates. As a result of polyglutamation of methotrexate caused by the folylpolyglutamylate enzyme, the duration of the cytotoxic effect of the drug substance in the cell increases.

Related product monographs

Title Information Source Document Type  
JYLAMVO Oral solution European Medicines Agency (EU) MPI, EU: SmPC
METHOTREXATE Solution for Injection Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
METHOTREXATE Tablets Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
METOJECT PEN Solution for injection in pre-filled pen Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Medicines in this ATC group

Australia (AU)

Austria (AT)

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Ecuador (EC)

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Israel (IL)

Japan (JP)

Lithuania (LT)

Malta (MT)

Netherlands (NL)

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Singapore (SG)

South Africa (ZA)

Spain (ES)

Tunisia (TN)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.