This brand name is authorized in Nigeria
The drug ESITRIM contains a combination of these active pharmaceutical ingredients (APIs):
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1
Sulfamethoxazole
UNII JE42381TNV - SULFAMETHOXAZOLE
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Sulfamethoxazole competitively inhibits the utilisation of para-aminobenzoic acid in the synthesis of dihydrofolate by the bacterial cell resulting in bacteriostasis. |
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2
Trimethoprim
UNII AN164J8Y0X - TRIMETHOPRIM
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Trimethoprim is a dihydrofolate reductase inhibitor, inhibiting the conversion of bacterial dihydrofolic acid to tetrahydrofolic acid, required for the synthesis of some amino acids. Its effects are considerably greater on the cells of micro-organisms than on the mammalian cells. |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| J01EE01 | Sulfamethoxazole and trimethoprim | J Antiinfectives for systemic use → J01 Antibacterials for systemic use → J01E Sulfonamides and trimethoprim → J01EE Combinations of sulfonamides and trimethoprim, incl. derivatives |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: NG | Registered Drug Product Database | Identifier(s): A11-1019 |
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