Chemical formula: C₁₄H₁₈N₄O₃ Molecular mass: 290.318 g/mol PubChem compound: 5578
Trimethoprim is a dihydrofolate reductase inhibitor, inhibiting the conversion of bacterial dihydrofolic acid to tetrahydrofolic acid, required for the synthesis of some amino acids. Its effects are considerably greater on the cells of micro-organisms than on the mammalian cells.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| J01EA01 | Trimethoprim | J Antiinfectives for systemic use → J01 Antibacterials for systemic use → J01E Sulfonamides and trimethoprim → J01EA Trimethoprim and derivatives |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| TRIMOPTIN Tablet | Health Products Regulatory Authority (IE) | MPI, EU: SmPC |
Trimethoprim is an active ingredient of these brands:
United States (US)Brazil (BR)
Canada (CA)Croatia (HR)
Cyprus (CY)Ecuador (EC)
Estonia (EE)Finland (FI)
Germany (DE)
Hong Kong (HK)Israel (IL)
Malta (MT)Mexico (MX)
Nigeria (NG)
Poland (PL)
Romania (RO)Singapore (SG)
South Africa (ZA)
Spain (ES)Tunisia (TN)Turkey (TR)United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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