This brand name is authorized in Australia, Cyprus, Hong Kong, Ireland, Israel, Lithuania, Malta, Mexico, Netherlands, New Zealand, Singapore, United Kingdom, United States, South Africa
The drug LANOXIN contains one active pharmaceutical ingredient (API):
1
Digoxin
UNII 73K4184T59 - DIGOXIN
|
Digoxin increases contractility of the myocardium by direct activity. The primary action of digoxin is specifically to inhibit adenosine triphosphatase, and thus sodium-potassium (Na+ - K+) exchange activity, the altered ionic distribution across the membrane resulting in an augmented calcium ion influx and thus an increase in the availability of calcium at the time of excitation-contraction coupling. The potency of digoxin may therefore appear considerably enhanced when the extracellular potassium concentration is low, with hyperkalaemia having the opposite effect. |
Below package inserts are available for further reading:
Title | Information Source | Document Type | |
---|---|---|---|
LANOXIN Solution for injection | FDA, National Drug Code (US) | MPI, US: SPL/PLR | |
LANOXIN Tablet | FDA, National Drug Code (US) | MPI, US: SPL/PLR | |
Lanoxin 125 Tablets | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
ATC code | Group title | Classification |
---|---|---|
C01AA05 | Digoxin | C Cardiovascular system → C01 Cardiac therapy → C01A Cardiac glycosides → C01AA Digitalis glycosides |
This drug has been assigned below unique identifiers within the countries it is being marketed:
Country | Identification scheme | Identifier(s) |
---|---|---|
Country: AU | Pharmaceutical Benefits Scheme | Identifier(s): 1322N, 2605D, 3164M |
Country: GB | Medicines & Healthcare Products Regulatory Agency | Identifier(s): 104259, 13615, 13641, 13665, 14280, 161967, 175676, 185886, 27766 |
Country: HK | Department of Health Drug Office | Identifier(s): 03780, 03795, 03798, 60869 |
Country: IE | Health Products Regulatory Authority | Identifier(s): 30570, 30597, 30627, 63649 |
Country: IL | מִשְׂרַד הַבְּרִיאוּת | Identifier(s): 1110 |
Country: LT | Valstybinė vaistų kontrolės tarnyba | Identifier(s): 1089040, 1090989 |
Country: MT | Medicines Authority | Identifier(s): AA1343/00601, AA565/02904, MA955/00701, MA955/00702, PI1438/03201A, PI1438/03202A |
Country: MX | Comisión Federal para la Protección contra Riesgos Sanitarios | Identifier(s): 28448 |
Country: NL | Z-Index G-Standaard | Identifier(s): 12129232, 12400378 |
Country: NL | Z-Index G-Standaard, PRK | Identifier(s): 15954, 1635, 5916, 5924, 5932 |
Country: NZ | Medicines and Medical Devices Safety Authority | Identifier(s): 660, 661, 662 |
Country: SG | Health Sciences Authority | Identifier(s): 00544P, 00547P, 01198P, 01203P |
Country: US | FDA, National Drug Code | Identifier(s): 59212-240, 59212-242, 59212-249, 70515-260, 70515-261, 70515-262, 70515-263, 71610-019 |
Country: ZA | Health Products Regulatory Authority | Identifier(s): J/6.3/302 |
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