METOJECT

This brand name is authorized in Austria, Canada, Ecuador, Estonia, Spain, Finland, France, Ireland, Israel, Japan, Netherlands, United Kingdom

Active ingredients

The drug METOJECT contains one active pharmaceutical ingredient (API):

1 Methotrexate UNII 3IG1E710ZN - METHOTREXATE SODIUM

Methotrexate (4-amino-10-methylfolic acid) is a folic acid antagonist which inhibits the reduction of folic acid and increase of tissue cells. Methotrexate enters the cell through an active transport mechanism of reduced folates. As a result of polyglutamation of methotrexate caused by the folylpolyglutamylate enzyme, the duration of the cytotoxic effect of the drug substance in the cell increases. Read about Methotrexate

Medication package inserts

Below package inserts are available for further reading:

Title	Information Source	Document Type
METOJECT PEN Solution for injection in pre-filled pen	Medicines & Healthcare Products Regulatory Agency (GB)	MPI, EU: SmPC

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code	Group title	Classification
L01BA01	Methotrexate	L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01B Antimetabolites → L01BA Folic acid analogues
Discover more medicines within L01BA01
L04AX03	Methotrexate	L Antineoplastic and immunomodulating agents → L04 Immunosuppressants → L04A Immunosuppressants → L04AX Other immunosuppressants
Discover more medicines within L04AX03

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
Country: CA	Health Products and Food Branch	Identifier(s): 02320029, 02454750, 02454769, 02454777, 02454831, 02454858, 02454866, 02454874
Country: EC	Agencia Nacional de Regulación, Control y Vigilancia Sanitaria	Identifier(s): 7287-MEE-0622
Country: EE	Ravimiamet	Identifier(s): 1697340, 1706486
Country: ES	Centro de información online de medicamentos de la AEMPS	Identifier(s): 71107, 71108, 71109, 71110, 71111, 72384, 73716, 73717, 73718, 73719, 78631, 78632, 78633, 78634, 78635, 78636, 78637, 78638, 78639, 78704
Country: FI	Lääkealan turvallisuus- ja kehittämiskeskus	Identifier(s): 098840, 160968, 168508, 168519, 168530, 168541, 168552, 380594, 428884, 458343, 469872, 545850, 560459, 571137, 573878, 581937
Country: FR	Base de données publique des médicaments	Identifier(s): 60129957, 60791708, 64019846, 64768062, 64951170, 66151519, 66253794, 66418655, 66727840, 67670463, 67791066, 68660276, 69310332, 69472195, 69991749
Country: GB	Medicines & Healthcare Products Regulatory Agency	Identifier(s): 245885, 245888, 245891, 245894, 245897, 245900, 245905, 245907, 245909, 245912, 373977, 373979, 373981, 376893, 376897, 376900, 377237, 377239, 377241, 377243, 381510, 381512, 381514, 381516
Country: IE	Health Products Regulatory Authority	Identifier(s): 13152, 13153, 13154, 13155, 13156, 32594, 32598, 32619, 32685, 32690, 32691, 32692, 32693, 32694
Country: IL	מִשְׂרַד הַבְּרִיאוּת	Identifier(s): 7451, 7452, 7453, 7454, 7455, 7458, 7459, 7460, 7461, 7462
Country: JP	医薬品医療機器総合機構	Identifier(s): 3999468G1028, 3999468G2024, 3999468G3020, 3999468G4027
Country: NL	Z-Index G-Standaard	Identifier(s): 15493199, 15493202, 15493210, 15493229, 15504980, 15617874, 15659291, 15659305, 15659313
Country: NL	Z-Index G-Standaard, PRK	Identifier(s): 141321, 141348, 141356, 141364, 141372, 141380, 141399, 141402, 141410, 141429, 141437, 141445, 141453, 141461, 141488, 141496, 141518, 141526