METOJECT

This brand name is authorized in Austria, Canada, Ecuador, Estonia, Finland, France, Ireland, Israel, Japan, Netherlands, Spain, UK.

Active ingredients

The drug METOJECT contains one active pharmaceutical ingredient (API):

1	Methotrexate UNII 3IG1E710ZN - METHOTREXATE SODIUM
	Methotrexate (4-amino-10-methylfolic acid) is a folic acid antagonist which inhibits the reduction of folic acid and increase of tissue cells. Methotrexate enters the cell through an active transport mechanism of reduced folates. As a result of polyglutamation of methotrexate caused by the folylpolyglutamylate enzyme, the duration of the cytotoxic effect of the drug substance in the cell increases.
	Read more about Methotrexate

Medication package inserts

Below package inserts are available for further reading:

Document	Type	Information Source
METOJECT PEN Solution for injection in pre-filled pen	MPI, EU: SmPC	Medicines & Healthcare Products Regulatory Agency (GB)

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC Group		Classification
L01BA01	Methotrexate	L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01B Antimetabolites → L01BA Folic acid analogues
Discover more medicines within L01BA01
L04AX03	Methotrexate	L Antineoplastic and immunomodulating agents → L04 Immunosuppressants → L04A Immunosuppressants → L04AX Other immunosuppressants
Discover more medicines within L04AX03

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
CA	Health Products and Food Branch	02320029, 02454750, 02454769, 02454777, 02454831, 02454858, 02454866, 02454874
EC	Agencia Nacional de Regulación, Control y Vigilancia Sanitaria	7287-MEE-0622
EE	Ravimiamet	1697340, 1706486
ES	Centro de información online de medicamentos de la AEMPS	71107, 71108, 71109, 71110, 71111, 72384, 73716, 73717, 73718, 73719, 78631, 78632, 78633, 78634, 78635, 78636, 78637, 78638, 78639, 78704
FI	Lääkealan turvallisuus- ja kehittämiskeskus	098840, 160968, 168508, 168519, 168530, 168541, 168552, 380594, 428884, 458343, 469872, 545850, 560459, 571137, 573878, 581937
FR	Base de données publique des médicaments	60129957, 60791708, 64019846, 64768062, 64951170, 66151519, 66253794, 66418655, 66727840, 67670463, 67791066, 68660276, 69310332, 69472195, 69991749
GB	Medicines & Healthcare Products Regulatory Agency	245885, 245888, 245891, 245894, 245897, 245900, 245905, 245907, 245909, 245912, 373977, 373979, 373981, 376893, 376897, 376900, 377237, 377239, 377241, 377243, 381510, 381512, 381514, 381516
IE	Health Products Regulatory Authority	13152, 13153, 13154, 13155, 13156, 32594, 32598, 32619, 32685, 32690, 32691, 32692, 32693, 32694
IL	מִשְׂרַד הַבְּרִיאוּת	7451, 7452, 7453, 7454, 7455, 7458, 7459, 7460, 7461, 7462
JP	医薬品医療機器総合機構	3999468G1028, 3999468G2024, 3999468G3020, 3999468G4027
NL	Z-Index G-Standaard	15493199, 15493202, 15493210, 15493229, 15504980, 15617874, 15659291, 15659305, 15659313
NL	Z-Index G-Standaard, PRK	141321, 141348, 141356, 141364, 141372, 141380, 141399, 141402, 141410, 141429, 141437, 141445, 141453, 141461, 141488, 141496, 141518, 141526