PERTRIPTYL

This brand name is authorized in Finland

Active ingredients

The drug PERTRIPTYL contains a combination of these active pharmaceutical ingredients (APIs):

1 Amitriptyline
UNII 26LUD4JO9K - AMITRIPTYLINE HYDROCHLORIDE

Amitriptyline is a tricyclic antidepressant and an analgesic. It prevents the re-uptake, and hence the inactivation of noradrenaline and serotonin at nerve terminals. Reuptake prevention of these monoamine neurotransmitters potentiate their action in the brain. This appears to be associated with the antidepressant activity.

Read about Amitriptyline
2 Perphenazine
UNII FTA7XXY4EZ - PERPHENAZINE

Perphenazine is a depressant which blocks dopamine receptors in the central nervous system. It binds to dopamine D1 and D2 receptors and inhibits their activity. Its antiemetic action is mainly due to the inhibition of D2 receptors in the center of the vomiting. Perphenazine also binds to alpha adrenergic receptors and in conjunction with G proteins activate the phosphatidylinositol-calcium system.

Read about Perphenazine

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code Group title Classification
N06CA01 Amitriptyline and psycholeptics N Nervous system → N06 Psychoanaleptics → N06C Psycholeptics and psychoanaleptics in combination → N06CA Antidepressants in combination with psycholeptics
Discover more medicines within N06CA01

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: FI Lääkealan turvallisuus- ja kehittämiskeskus Identifier(s): 555649, 555680

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