This brand name is authorized in Austria, Australia, Brazil, Ecuador, Estonia, Spain, Finland, France, Netherlands, New Zealand, Romania, South Africa
The drug RENITEC contains one active pharmaceutical ingredient (API):
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1
Enalapril
UNII 9O25354EPJ - ENALAPRIL MALEATE
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Enalapril is hydrolysed via hepatic CES 1 to the active metabolite enalaprilat, which acts as an ACE inhibitor. ACE is a peptidyl dipeptidase which catalyses the conversion of angiotensin I to the vasoconstrictor substance angiotensin II and hence inhibition of ACE results in decreased plasma angiotensin II. This also leads to increased plasma renin activity and decreased aldosterone secretion. The mechanism of action of enalapril is therefore primarily via the suppression of the RAAS. However, ACE is identical to kininase II, and so enalapril may also exert its effects by blocking the degradation of bradykinin, a potent vasodepressor peptide. |
Below package inserts are available for further reading:
| Title | Information Source | Document Type | |
|---|---|---|---|
| RENITEC Tablet | Pharmaceutical Benefits Scheme (AU) | MPI, Generic |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C09AA02 | Enalapril | C Cardiovascular system → C09 Agents acting on the renin-angiotensin system → C09A ACE inhibitors, plain → C09AA ACE inhibitors, plain |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: AU | Pharmaceutical Benefits Scheme | Identifier(s): 1368B, 1369C |
| Country: BR | Câmara de Regulação do Mercado de Medicamentos | Identifier(s): 525501901113314, 525501903116310, 525501904112319 |
| Country: EC | Agencia Nacional de Regulación, Control y Vigilancia Sanitaria | Identifier(s): 367200813 |
| Country: EE | Ravimiamet | Identifier(s): 1074215, 1074226, 1074259, 1371080 |
| Country: ES | Centro de información online de medicamentos de la AEMPS | Identifier(s): 57768, 57773 |
| Country: FI | Lääkealan turvallisuus- ja kehittämiskeskus | Identifier(s): 091686 |
| Country: FR | Base de données publique des médicaments | Identifier(s): 64371242, 68128273 |
| Country: NL | Z-Index G-Standaard, PRK | Identifier(s): 21075 |
| Country: NZ | Medicines and Medical Devices Safety Authority | Identifier(s): 13617, 3449, 3450 |
| Country: RO | Agenția Națională a Medicamentului și a Dispozitivelor Medicale | Identifier(s): W68244001, W68245001, W68246001 |
| Country: ZA | Health Products Regulatory Authority | Identifier(s): T/7.1.3/164, T/7.1.3/165, T/7.1.3/166 |
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