TREXAN

This brand name is authorized in Estonia, Finland, Lithuania, Poland, Singapore, Turkey.

Active ingredients

The drug TREXAN contains one active pharmaceutical ingredient (API):

1	Methotrexate UNII YL5FZ2Y5U1 - METHOTREXATE
	Methotrexate (4-amino-10-methylfolic acid) is a folic acid antagonist which inhibits the reduction of folic acid and increase of tissue cells. Methotrexate enters the cell through an active transport mechanism of reduced folates. As a result of polyglutamation of methotrexate caused by the folylpolyglutamylate enzyme, the duration of the cytotoxic effect of the drug substance in the cell increases.
	Read more about Methotrexate

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC Group		Classification
L01BA01	Methotrexate	L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01B Antimetabolites → L01BA Folic acid analogues
Discover more medicines within L01BA01

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
EE	Ravimiamet	1228126, 1276972, 1276994, 1277018, 1688700, 1688711, 1688722, 1688733, 1688744, 1688766, 1722024, 1724082, 1727085, 1727096, 1833397, 1847651, 1857056, 1857067, 1857078, 1857089, 1857090, 1857102, 1857113, 1857124, 1857135, 1857146, 1857157, 1857168, 1857179, 1857180, 1857191, 1857203, 1857214, 1857225, 1857236, 1857247
FI	Lääkealan turvallisuus- ja kehittämiskeskus	055209, 101953, 133568, 378114, 480111, 528941, 556002, 573671, 585270
LT	Valstybinė vaistų kontrolės tarnyba	1077472, 1077473, 1077474, 1081095, 1081096, 1081097, 1081098, 1081099, 1081100, 1081101, 1081102, 1081103, 1081104, 1081105, 1081106, 1091010, 1093140, 1093141, 1093142, 1093143, 1093144, 1093145, 1093146, 1093147, 1093148, 1093149, 1093150, 1093151, 1093152, 1093153, 1093154, 1093155, 1093156, 1093157, 1093158, 1093159, 1093160, 1093161, 1093162, 1093163, 1093164, 1093165
PL	Rejestru Produktów Leczniczych	100067751, 100216056, 100349455, 100349461
SG	Health Sciences Authority	00241P
TR	İlaç ve Tıbbi Cihaz Kurumu	8699694010086