ZIRABEV

This brand name is authorized in Austria, Canada, Estonia, Spain, France, Croatia, Ireland, Italy, Lithuania, Netherlands, New Zealand, Poland, Romania, Turkey, United Kingdom, United States

Active ingredients

The drug ZIRABEV contains one active pharmaceutical ingredient (API):

1 Bevacizumab UNII 2S9ZZM9Q9V - BEVACIZUMAB

Bevacizumab binds to vascular endothelial growth factor (VEGF), the key driver of vasculogenesis and angiogenesis, and thereby inhibits the binding of VEGF to its receptors, Flt-1 (VEGFR-1) and KDR (VEGFR-2), on the surface of endothelial cells. Neutralising the biological activity of VEGF regresses the vascularisation of tumours, normalises remaining tumour vasculature, and inhibits the formation of new tumour vasculature, thereby inhibiting tumour growth. Read about Bevacizumab

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code	Group title	Classification
L01FG01	Bevacizumab	L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01F Monoclonal antibodies and antibody drug conjugates → L01FG VEGF/VEGFR (Vascular Endothelial Growth Factor) inhibitors
Discover more medicines within L01FG01

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
Country: CA	Health Products and Food Branch	Identifier(s): 02489430, 02489449
Country: EE	Ravimiamet	Identifier(s): 1789432, 1789443
Country: ES	Centro de información online de medicamentos de la AEMPS	Identifier(s): 1181344001, 1181344002
Country: FR	Base de données publique des médicaments	Identifier(s): 64224872
Country: GB	Medicines & Healthcare Products Regulatory Agency	Identifier(s): 384843, 384855
Country: IT	Agenzia del Farmaco	Identifier(s): 047629011, 047629023
Country: LT	Valstybinė vaistų kontrolės tarnyba	Identifier(s): 1087076, 1087077
Country: NL	Z-Index G-Standaard, PRK	Identifier(s): 76910, 76929
Country: NZ	Medicines and Medical Devices Safety Authority	Identifier(s): 21604
Country: PL	Rejestru Produktów Leczniczych	Identifier(s): 100416884
Country: RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	Identifier(s): W66686001, W66686002
Country: TR	İlaç ve Tıbbi Cihaz Kurumu	Identifier(s): 8681308771087, 8681308771094
Country: US	FDA, National Drug Code	Identifier(s): 0069-0315, 0069-0342