Nausea, vomiting

Active Ingredient: Perphenazine

Indication for Perphenazine

Population group: only adults (18 - 65 years old)

For this indication, competent medicine agencies globally authorize below treatments:

8-24 mg in 3 divided doses daily

Route of admnistration

Oral

Defined daily dose

8 - 24 mg

Dosage regimen

From 2.667 To 8 mg 3 time(s) per day every day

Detailed description

8 to 16 mg daily in divided doses; 24 mg occasionally may be necessary; early dosage reduction is desirable.

Active ingredient

Perphenazine

Perphenazine is a depressant which blocks dopamine receptors in the central nervous system. It binds to dopamine D1 and D2 receptors and inhibits their activity. Its antiemetic action is mainly due to the inhibition of D2 receptors in the center of the vomiting. Perphenazine also binds to alpha adrenergic receptors and in conjunction with G proteins activate the phosphatidylinositol-calcium system.

Read more about Perphenazine

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