PERPHENAN Film coated tablet Ref.[8267] Active ingredients: Perphenazine

Revision Year: 2016  Publisher: Taro Pharmaceutical Industries Ltd, 14 Hakitor Street, Haifa Bay, 2624761

Product name and form

Perphenan 4mg.

Perphenan 8mg.

Pharmaceutical Form

Film coated tablet.

Perphenan 4 mg: White, round, bi-convex, coated tablets. Both sides plain.

Perphenan 8 mg: Gray, round, bi-convex, coated tablets. Both sides plain.

Qualitative and quantitative composition

Perphenan 4mg: Each tablet contains 4mg Perphenazine.

Perphenan 8mg: Each tablet contains 8mg Perphenazine.

Active Ingredient Description
Perphenazine

Perphenazine is a depressant which blocks dopamine receptors in the central nervous system. It binds to dopamine D1 and D2 receptors and inhibits their activity. Its antiemetic action is mainly due to the inhibition of D2 receptors in the center of the vomiting. Perphenazine also binds to alpha adrenergic receptors and in conjunction with G proteins activate the phosphatidylinositol-calcium system.
List of Excipients

Perphenan 4 mg:

Lactose monohydrate
Corn starch
Microcrystalline cellulose
Gelatin
Magnesium stearate

Coating contains:

Polyvinyl alcohol-partially hydrolyzed
Titanium dioxide
PEG 3350
Talc

Perphenan 8 mg:

Lactose monohydrate corn starch
Microcrystalline cellulose
Gelatin
Sodium starch
Glycolate
Magnesium stearate

Coating contains:

Hypromellose
Titanium dioxide
Polydextrose
PEG
Black iron oxide

Pack sizes and marketing

Perphenan 4 mg: PVC aluminum foil blister pack containing 30 tablets or 1000 tablets.

Perphenan 8 mg: PVC aluminum foil blister pack containing 20 tablets, 30 or 1000 tablets.

Nor all pack sizes may be marketed.

Marketing authorization holder

Taro Pharmaceutical Industries Ltd, 14 Hakitor Street, Haifa Bay, 2624761

Marketing authorization dates and numbers

Perphenan 4 mg: 015.38.24729

Perphenan 8 mg: 123.49.24730

 
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